WHAT CAUSES NASAL POLYPS AND NASAL POLYPOSIS?
Nasal polyps have an unknown cause. Among the supposed causes of nasal polyps, we can mention:
– Injury of the nasal mucous that has the function of entry door for irritating allergens (germs, chemical and physical stimuli) which are responsible for the transformation of the healthy mucous into nasal polyps.
– Allergic inflammation of the nasal mucous related to specific cells, eosinophil cells, with the production of specific antibodies (IgE) that are the starting mechanism of the formation of nasal polyps.
– Intolerance to acetylsalicylic acid (aspirin) and to other anti-inflammatory medicine non-steroidal; in these clinical cases a chronic inflammatory process of the nasal and bronchial mucous develops and it is related to molecules that belong to the arachidonic acid especially leukotrienes.
– Self-destructive immunologic mechanism of the nasal mucous by the antibodies produced both from nasal mucous and from blood.
– Alterations of the nasal ventilation of the nasal cavities and paranasal cavities caused by an inappropriate oxygenation of cells and their transformation in inflammatory cells (frequent situations are: turbinates hypertrophy, deviated septum, communication anomalies between the nose and paranasal sinuses).
– Malfunction of the neuro-vegetative system that is part of the nasal mucous by irritating and creating the inflammatory processes causing the presence of nasal polyps.
– Inhalation of some products used in the industrial processing, with an increasing risk factor for specific workers (carpenters, cementers, tillers, plasterers, glassmakers, papermakers, fabric makers, tobacco workers).
– Chronic infection caused by bacteria and fungi damaging the mucous and as a consequence an inflammatory circle of demand that leads to nasal polyps.
– Hereditariness and familiarity genetic factors for nasal polyposis among the members of the same generation of the future ones